Compendial techniques and methods

Physical and physicochemical testing methods

Clarity and degree of opalescence of liquids
Degree of coloration of liquids
Potentiometric determination of pH
Relationship between reaction of solution, approximate pH and colour of certain indicators
Relative density
Refractive index
Optical rotation
Viscosity-rotating viscosity meter method
Distillation range
Boiling point
Melting point – capillary method
Freezing point
Potentiometric titration
Absorption spectrophotometry, infrared
Absorption spectrophotometry, ultraviolet and visible
Thin-layer chromatography
Gas chromatography GD – FID
Gas chromatography Headspace – FID
Liquid chromatography
- HPLC – UV/VIS
- HPLC – UV/VIS (DAD)
- HPLC – RI
- HPLC – fluorescence
Loss on drying
Conductivity
Identification
Identification reactions of ions and functional groups
Identification of fatty oils by thin-layer chromatography
Odour
Limit tests
- Ammonium
- Arsenic
- Calcium
- Chlorides
- Magnesium
- Magnesium and alkaline-earth metals
- Heavy metals
- Iron
- Phosphates
- Potassium
- Sulphates
- Sulphated ash
- Nickel in polyols
Total ash
Aluminium
Free formaldehyde
Composition of fatty acids by gas chromatography
Assay
Acid value
Ester value
Hydroxyl value
Iodine value
Peroxide value
Saponification value
Unsaponifiable matter
Determination of primary aromatic amino-nitrogen
Complexometric titrations
Water: semi-micro determination
Water micro determination
Ethanol content and alcoholimetric tables

Microbiological examination of non-sterile products: microbial enumeration tests
Microbiological examination of non-sterile products: test for specified micro-organisms
Microbiological assay of antibiotics
Efficacy of preservation