Physical and physicochemical testing methods

  • Clarity and degree of opalescence of liquids
  • Degree of coloration of liquids
  • Potentiometric determination of pH
  • Relationship between reaction of solution, approximate pH and colour of certain indicators
  • Relative density
  • Refractive index
  • Optical rotation
  • Viscosity-rotating viscosity meter method
  • Distillation range
  • Boiling point
  • Melting point – capillary method
  • Freezing point
  • Potentiometric titration
  • Absorption spectrophotometry, infrared
  • Absorption spectrophotometry, ultraviolet and visible
  • Thin-layer chromatography
  • Gas chromatography GD – FID
  • Gas chromatography Headspace – FID
  • Liquid chromatography
    • HPLC – UV/VIS
    • HPLC – UV/VIS (DAD)
    • HPLC – RI
    • HPLC – fluorescence
  • Loss on drying
  • Conductivity
  • Identification
  • Identification reactions of ions and functional groups
  • Identification of fatty oils by thin-layer chromatography
  • Odour
  • Limit tests
    • Ammonium
    • Arsenic
    • Calcium
    • Chlorides
    • Magnesium
    • Magnesium and alkaline-earth metals
    • Heavy metals
    • Iron
    • Phosphates
    • Potassium
    • Sulphates
    • Sulphated ash
    • Nickel in polyols
  • Total ash
  • Aluminium
  • Free formaldehyde
  • Composition of fatty acids by gas chromatography
  • Assay
  • Acid value
  • Ester value
  • Hydroxyl value
  • Iodine value
  • Peroxide value
  • Saponification value
  • Unsaponifiable matter
  • Determination of primary aromatic amino-nitrogen
  • Complexometric titrations
  • Water: semi-micro determination
  • Water micro determination
  • Ethanol content and alcoholimetric tables

Biological

  • Microbiological examination of non-sterile products: microbial enumeration tests
  • Microbiological examination of non-sterile products: test for specified micro-organisms
  • Microbiological assay of antibiotics
  • Efficacy of preservation

Methods in pharmacognosy

  • Dry residue of extracts
  • Loss on drying of extracts
  • Visual examination of herbals
  • Microscopically examination of herbals

Pharmaceutical technical procedures

  • Disintegration of tablets and capsules
  • Dissolution test for solid dosage form
  • Uniformity of mass of single-dose preparations
  • Uniformity of content of single-dose preparations
  • Friability of uncoated tablets
  • Resistance to crushing of tablets
  • Apparent volume
  • Test for extractable volume of parenteral preparations
  • Uniformity of mass of delivered doses from multidose containers
  • Bulk density and tapped density of powders
  • Sieving of powders